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Artificial Reproductive Technologies (ART) on-a-chip

Summary

Artificial Reproductive Technologies (ART) on-chip envision to revolutionise artificial reproductive technologies by utilising a proprietary custom-built micro-optofluidic platform.

Supervisor

Associate Professor Stefano Palomba.

Research location

School of Physics

Synopsis

Artificial Reproductive Technologies (ART) underpin genetic and production gains in animal agriculture and form the basis of the treatment of infertility in wildlife, including species at risk repopulation, companion animals and human reproduction. Many of the steps in ARTs involve high human labour and technical input to manipulate gametes and embryos in space as well as assessing their quality. Direct pipetting of these reproductive structures by human operators or banks of expensive flow cytometers are the accepted norm. ART-on-chip promises to revolutionise artificial reproductive technologies by utilising a micro-optofluidic platform to facilitate, and depending on the application, integrate, male and/or female gamete assessment, selection and combination for fertilisation, then subsequent support and manipulation of resultant embryos for frozen storage.

Additional information

  • Project keywords: micro-optofluidic, optical trapping, biophotonics, Artificial Reproductive Technologies    
  • Additional supervisors: Prof Simon de Graaf and Dr Daniele Vigolo
  • Program type: Both PhD and Mphil

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Opportunity ID

The opportunity ID for this research opportunity is 3560

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